Equipment
Syncropatch 384

High Throughput automated planar patch clamp ideal for screening of modulators of ion channels and electrogenic transporters. Also useful for the functional characterization of complex cell populations. Cells must be in suspension to be used with this technique
MaxOne microelectrode array (MEA)

MaxOne is a CMOS-based high density microelectrode array (HD-MEA), an electrical imaging system for neuroscience, drug discovery, and cell assessment applications. MaxOne captures high-quality signals at sub cellular resolution from acute tissue experiments and long-term culture experiments.
Key features
- 26,400 electrodes (9.3×5.45 sq-μm, 17.5 μm pitch)
- 1020 low-noise readout channels
- 32 stimulation channels
- Large sensor area (3.85×2.10 sq-mm)
HEKA Patch Clamp rig

HEKA EPC10-USB amplifier
SliceScope Pro 1000 (Scientifica UK) with motorized XY stage
Scientifica SciCam Pro camera
GFP and mCherry / Texas Red Filter Sets
DIC condenser and IR ilumination
Suitable for:
Whole cell and single channel patch clamp
Patch clamp in tissue slices
GFP and mCherry -based imaging and cell identification
Sutter Dual Headstage Setup
Dual headstage to measure connected cells in parallel
Dynamic clamp
Integrated IgorPro software
Ratiometric live-imaging capabilities to study quantitative Calcium and Magnesium dynamics using pE-800-fura CoolLED
Axon Patch Clamp rig

Axon CNS Multiclamp 700B
Axon CNS Digidata 1440A
Upright Olympus microscope BX51WI with FITC / EGFP filter
Leica DFC 350FX camera
Suitable for:
Whole cell patch clamp
Fluo-4 / EGFP-based imaging and cell identification
Two electrodes voltage clamp (TEVC)

Ussing Chamber (6 channels)
Suitable for measurement of epithelial membrane properties in tissue samples or cell monolayer grown in permeable support
Cell culture
