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High Throughput automated planar patch clamp ideal for screening of modulators of ion channels and electrogenic transporters. Also useful for the functional characterization of complex cell populations. Cells must be in suspension to be used with this technique
HEKA EPC10-USB amplifier
SliceScope Pro 1000 (Scientifica UK) with motorized XY stage
Scientifica SciCam Pro camera
GFP and mCherry / Texas Red Filter Sets
DIC condenser and IR ilumination
Suitable for:
Whole cell and single channel patch clamp
Patch clamp in tissue slices
GFP and mCherry -based imaging and cell identification
Axon CNS Multiclamp 700B
Axon CNS Digidata 1440A
Upright Olympus microscope BX51WI with FITC / EGFP filter
Leica DFC 350FX camera
Suitable for:
Whole cell patch clamp
Fluo-4 / EGFP-based imaging and cell identification
Suitable for measurement of epithelial membrane properties in tissue samples or cell monolayer grown in permeable support